Keeping and administering veterinary medication to a horse : good practices
When not correctly stored and used, veterinary medication contain active ingredients which may present a risk to horse and human health. This fact sheet will give an overview of good practices to observe when keeping and storing veterinary medicines, and also when administering them.
- Ensuring traceability of veterinary medication used
- Keeping veterinary medication securely
- Keeping veterinary medication correctly
- Knowledge of the ways and good practices regarding administering medication
- Declaring any side effects
- To remember
- Legislation references
Ensuring traceability of veterinary medication used
Most veterinary medicines are subject to compulsary prescription : they must therefore be prescribed by your treating vet prior to administration. Prescriptions should be kept for 5 years. Any medical care, veterinary acts and treatment administered should be recorded in the farm register.
Keeping veterinary medication securely
Storage of medication should be secure so as to avoid being used or tampered with by unqualified persons. The goal is to protect human and horse health, as some medicines can present a danger when used incorrectly.
They should therefore be stored in a dedicated location, seperate from human medication, and access should be controlled. In riding schools, it is mandatory to store them under lock and key.
Keeping veterinary medication correctly
Optimal preservation of veterinary medication is essential to maintain the quality and to avoid:
- A decrease of their effectiveness
- The appearance of unwanted side-effects, or even toxicity for horses
A certain number of parameters can influence the quality of a medicine:
In order to ensure optimal preservation of medicines it is essential to store them in suitable conditions.
What temperature ?
Medicines should be stored away from sources of excessive heat and cold.
Some medicines require storage in a refrigerator (between 2°C and 8°C). This is the case for vaccines and serums and some injectable solutions for example. It is noted on the label and the information leaflet. When in doubt, ask your treating vet. In the refigerator, the bottles should not be kept against the sides of the refrigerator, (possibility of freezing), nor stored in the door (higher temperatures).
In extreme heat, the bottles should not be out of the refrigerator for any length of time : it is advisable to fill the seringe and put the bottle back in the refrigerator immediately.
Other medicines may be stored at room temperature : in this case there is no specific note on the label or in the leaflet. However, in no case should medicines be exposed to temperatures above 25°C/30°C.
In a clean storage place
To keep medicines away from light, dust and damp, they should be stored in a clean storage place (e.g. a cupboard equipped with doors) and be kept in their original packaging (e.g. bottle kept in its carton).
How long can medicines be kept for ?
When the medicine has not been opened, it can be kept until its use by date if the conditions it is kept in are suitable.
Once it has been opened, it should be used within 28 days following opening, unless the label says differently. It is therefore important to note on the bottle the date when it was opened.
Disposal of outdated medication and equipment for administration
Care products and medication past the use by date can be a risk for humans, animals and the environment. They are classified according to the risk they represent and should be sorted before disposal via the proper waste circuit. It is therefore important to manage veterinary product disposal properly.
Knowledge of the ways and good practices regarding administering medication
As a horse owner, you may be in the position of administering medication prescribed by the vet yourself.
During the veterinary examination
Some medicines can come in different galenic forms (injectable solutions, oral powder…). It is important to discuss the treatment with your vet, so as to give the treatment in the form most suited to the horse’s living conditions, his behaviour, and the experience of the person administering the medication. This will enable the treatment to be correctly followed (treatment adapted to the prescription and to the way the carer uses it).
It is also essential to have understood every item on the prescription:
- Posology : dosage of medication to be administered
- Method of administration (e.g. injecting an unsuitable medicine into a vein can be fatal)
- Frequency of administration : (e.g. once a day)
- Length of time over which the treatment should be continued
It is also important to have an estimation of the animal’s weight for the dosage, so as to avoid overdosing (which could have negative side-effects) or on the contrary underdosing, (less effective):
- For adult horses (> 3 years old) : the estimation can be made from the height at the withers, and the heartgirth. There is a simulation tool here.
- A foal’s weight can be estimated using a measuring tape.
Before administering medication
It is essential to follow the instructions on the prescription very carefully in order to guarantee the effectiveness of the treatment and innocousness.
Risk if the treatmnt is underdosed, the duration is shortened, or the frequency decreased | Risk when there is overdosing, increase of the duration or increase of the frequency |
---|---|
Failure of the treatment | Side-effects may occur |
Parasites becoming resistant to wormers → efficiency of wormers decreases, and it becomes more difficult to treat worm infestation subsequently | Increase in the doping period with an impact on competition paticipation |
Devlopment of resistance to antibiotics:
| Increase in the time required before slaughtering for horses destined for the meat sector, or for those producing milk |
Which horse can you administer medication to ?
With regard to medication requiring a prescription, it can only be administered to the horse mentioned on the prescription. It is prohibited and even dangerous to administer the said medicine to another equine, without a new prescription from your vet.
Administering medication systemically
The active ingredient(s) of the medicine then transit via the bloodstream to reach their target location.
Administering medication orally
A certain number of medicines are available for oral distribution in different forms : oral pastes, tablets, powders to be mixed into the feed…
Prior to administering a paste or a diluted powder by means of a seringe, the horses mouth should be emptied, and rinsed out with water, to avoid the horse spitting it out. The product should be administered progressively near the base of the horse’s tongue.
When medication in the form of a powder is administered mixed into the horse’s feed, it is advisable to dampen it so that the horse does not blow it away. It is then important to make sure the horse is eating correctly, if not either change the administration method (directly in the mouth via a seringe) or improve palatability of the feed (sugary feed).
To avoid other horses accidentally ingesting the medicine, even in very small doses, and thus avoiding accidental doping, it is recommended:
- To avoid giving the powder directly in built-in mangers, which can be difficult to clean out, instead feed the horse in a bucket.
- Use a different bucket for each horse, or clean it out thoroughly between horses.
- Isolate the horse from the others in the same group at feed time.
arenteral administration of medication : injections
Injections in horses are mainly intramuscular (IM) or intraveinous (IV). The main advantage compared to administering orally, is a lower risk of cross-contamination between horses. They also permit better dosing. They do however require a basic lnowledge of the horse’s anatomy.
Administering medication locally
This method of adminstration is only used for certain specific ailments. The risk of side-effects are lesser than a systemic approach, as the medicine is directly in contact with the target location. There are different methods of administration:
- Cutaneous administration, used mainly for any dermatological ailments : gels, creams, shampoos, solutions to be applied directly to the skin in the form of sprays or pour-on solutions.
- Administration to the eye (cream or eye-drops) used to treat ophthalmic disorders (e.g. ulcers, uveitis).
- The pulmonary route eanbles you to administer medication in the form of aerosols (in the case of asthma for example)
Declaring any side effects
When you notice any side-effects o, your horse, following the administration of veterinary medicaton, or if you suspect the treatment is not effective, or an environmental issue, it is important to declare it:
- Either to your trearing vet
- Or directly on the online declaration portal of the National Veterinary Medication page
The purpose being to quickly detect any adverse effects, whether already known or not, in order to take adequate measures : adding a cautionary note or even removing the marketing authorization for the said medication.
Likewise, if you notice any side-effects on human beings after being exposed to veterinary medication, you should also declare it :
- Either to your trearing doctor
- Or directly on the Minstry of health’s online portal for the declaration of unwanted sanitary occurrences
• Fourteen cases linked to the ButoxNDV range (containing the insecticide deltamethrin) showed cutaneous eruptions, eye or respiratory irritation. The suitable dilution should be respected before using these products, and the precautions for use stated in the leaflet should be taken : protective clothing, avoid spraying against a wind…
• Eleven case of ingestion of PrascendNDV, containing pergolid and used to treat horses with Cushing’s syndrome. The tablets were ingested accidentally, either by absobing food containing pergolid destined for a horse, either by mixing it up with human medication. The side-effects observed were mainly digestive, general, cardiovascular, and neurological.
► More information can be found on the fact sheet : preventing accidental ingestion of medication for horses.
To remember
Veterinary medication is kept in a dedicated location, with controlled access. In a riding school this location should be kept under lock and key.
To guarantee effectiveness and innocuity, any veterinary medication is kept away from excessive heat or cold, away from light , damp and dust. Some drugs such as serums and vaccines required refrigeration.
Medicines past the use by date should be disposed of and not used. Once opened, they can be used for 28 days unless otherwise stated on the package.
Strictly respecting the instructions on the prescription will restrict side-effects, and guarantee the effectiveness of the treatment and limit the development of resistances (for antibiotcs and wormers).
The method of administering the drug should be chosen, wherever possible, in agreement with your treating vet, so as to ensure that the treament is follwed correctly.
To improve knowledge with regard to medication available for horses, any unusual side-effects should be declared.
Legislation references
- Articles L. 5146-1 and L. 5146-2 of the Public health Code
- Articles L. 205-1 and L.231-2 of the Rural and Fishing code
- Decree dated 5th June 2000 relating to the farm register
- Decree dated 22nd July 2015 relating to good practices for usage of drugs containing one or several antibiotic substances in veterinary medicine
Know more about our authors
- Translated from french by : Karen DUFFY Translator
- Marie DELERUE Veterinarian - development engineer IFCE
Bibliography
- Site internet de l’Agence Nationale du Médicament Vétérinaire, Anses
- Plaquette Conservation des médicaments vétérinaires, ANMV-Anses
- Cas d’expositions humaines à des médicaments vétérinaires, Etude retrospective des cas enregistrés dans la base de pharmacovigilance vétérinaire en 2018, rapport d’étude, Anses